What is the conversion factor for Codeine to Morphine?

The conversion factor between codeine and morphine can vary depending on the specific context and individual patient factors, but a commonly used guideline is:

• Codeine to Morphine Conversion: Codeine is approximately 10 times less potent than morphine.

This means that, in general, 10 mg of codeine is roughly equivalent to 1 mg of morphine when both are taken orally.

Example Conversion:

• 100 mg of Codeine is roughly equivalent to 10 mg of Morphine.

Conversion Factors:

• Oral Codeine to Oral Morphine: 10 mg of oral codeine ≈ 1 mg of oral morphine.

Important Considerations:

• Individual Variability: Individual responses to opioids can vary due to differences in metabolism, tolerance, and other factors.

• Formulations and Routes of Administration: The potency and effects can differ based on whether the medication is taken orally, intravenously, or by other routes.

When converting from one opioid to another, it's crucial to consult with a healthcare provider to ensure accurate dosing and to account for individual patient needs and responses.