What are the signs of an opiate overdose?
Date created:
Wednesday, December 3, 2025
Here’s a direct, clinical, no-nonsense list of the signs of an opioid overdose. These are the ones that matter in real-world situations.
Major Signs of an Opioid Overdose
1. Breathing problems (the most important sign)
Slow, shallow, or irregular breathing
Breaths spaced far apart
No breathing
Snoring or gurgling (“death rattle”) sounds
2. Extreme unresponsiveness
Won’t wake up
Doesn’t respond to shouting or shaking
Limp body
3. Pinpoint pupils
Extremely small pupils (“pinpoints”)
Very reliable sign if opioids are the main cause
4. Cyanosis (lack of oxygen)
Blue or gray lips
Blue fingernails
Pale or ashy skin tone
5. Cold, clammy skin
Skin feels cool or sweaty
Weak or absent pulse
6. Slow or stopped heart rate
Weak pulse
No detectable pulse in severe cases
Secondary Signs (Not always present, but common)
Vomiting
Seizure-like movements
Choking sounds
Very slow to no response when you rub the sternum (sternal rub)
FAST Action Steps (what to do)
If you see ANY of the above:
Call 911 immediately
Administer naloxone (Narcan) if available
Rescue breathing if not breathing
Stay with them until help arrives
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